Cristina R. Ispas

Thesis: Biosensors based on inorganic nanoparticles with

 biomimetic properties: biomedical applications and in

 vivo cytotoxicity measurements 

Research: - Electrochemical studies of ceria as electrode material for sensing and biosensing applications

- Cerium oxide and titanium oxide nanomaterials for biosensors design and enzyme immobilization

 - Electrochemical sensors for monitoring neurological activity during ischemic brain injury

 - Monitoring the level of brain glutamate with implantable Pt microbiosensors

 - Investigating the potential risk posed by engineered nanomaterials using zebrafish embryos as a toxicological target  

Awards and honors:

Patent:

US Patent: Reagentless ceria based colorimetric sensor, 2019

  E. Silvana Andreescu, M. Ornatska, C.R. Ispas and D. Andreescu

       patents.google.com/patent/US20120315659A1/en

Publications:

[10]  Glutamate oxidase biosensor based on mixed ceria and titania nanoparticles for the detection of glutamate in hypoxic environments

   E.R. Ozel, C.R. Ispas, M. Ganesana, J.C. Leiter, and S. Andreescu

    Biosens. Bioelectron., 52, 2014, 2240-2249

https://doi.org/10.1016/j.bios.2013.08.054

[9]  Review: Recent developments in enzyme-based biosensors for biomedical applications 

   C.R. Ispas, G. Crivat, and S. Andreescu

    Anal. Lett., 45, 2012, 168-186, (Invited)

https://doi.org/10.1080/00032719.2011.633188 

[8]  Chapter 9 - Nanostructured Bioassemblies for Environmental Bioremediation

S. Andreescu, C. Ispas, A. Scangas, and L. Stanciu

in: Nanotechnology for Environmental Decontamination, Eds. M.K. Ram, S. Andreescu and H. Ding, McGraw-Hill, 2011 

https://www.accessengineeringlibrary.com/content/book/9780071702799/chapter/chapter9

[7]  Biomagnetic capsules for easy removal of phenol and bisphenol A

  C.R. Ispas, M.T. Ravalli, A. Steere, and S. Andreescu 

    Water Res., 44, 2010, 1961-1969

 https://doi.org/10.1016/j.watres.2009.11.049 

[6]  Toxicity and developmental defects of different sizes and shape nickel nanoparticles in zebrafish

  C. Ispas, D. Andreescu, A. Patel, D.V. Goia, K. Wallace and S. Andreescu

    Environ. Sci. Technol., 43(16), 2009, 6349-6356

https://doi.org/10.1021/es9010543 

[5]  Enzyme functionalized mesoporous silica for bioanalytical applications 

  C. Ispas, I. Sokolov, and S. Andreescu

    Anal. Bioanal. Chem., 393(2), 2009, 543-554

https://doi.org/10.1007/s00216-008-2250-2 

 (Top 9 most cited articles published in 2009)

[4]  Applications of advanced nanomaterials for environmental monitoring 

  S. Andreescu, J. Njagi, C. Ispas, and M. Ravalli

    J. Environ. Monit., 11, 2009, 27-40. (Critical review)

https://doi.org/10.1039/B811063H 

(JEM Spotlight article, Top 10 most accessed articles in 2009 and 2010) 

[3]  Chapter VII - Nanostructured materials for enzyme immobilization and biosensors

S. Andreescu, J. Njagi, and C. Ispas 

in: The New Frontiers of Organic and Composite Nanotechnology,  (Eds. V. Erokin, M. K. Ram and O. Yavuz), Elsevier, 2008, 355-394 

https://doi.org/10.1016/B978-008045052-0.50009-9

[2]  Mixed Ceria Based Metal Oxides Biosensor for Operation in Oxygen Restrictive Environments 

  J. Njagi, C. Ispas, and S. Andreescu

    Anal. Chem., 80(19), 2008, 7266-7274

   https://doi.org/10.1021/ac800808a 

[1]  Electrochemical Studies of ceria as electrode material for sensing and biosensing applications 

  C. Ispas, J. Njagi, and S. Andreescu

    J. Electrochem. Soc., 155(8), 2008, F169-F176

https://doi.org/10.1149/1.2936178 

Conferences:

     - invited speaker -"Enzyme based sensors and colorimetric detection kits for clinical monitoring

Beckman Coulter Headquarters, Brea CA, April 30, 2010 

     - invited speaker - "Nanomaterials for enzyme immobilization and biosensor design"

 Department of Physiology Johns Hopkins University School of Medicine, Baltimore, MD, March 10, 2010 

  - "Inexpensive, rapid, and portable bioassay for rapid detection of estrogenic activity", 

The 240th ACS National Meeting, Boston MA, August 22-26, 2010  

The 240th ACS National Meeting, Boston MA, August 22-26, 2010  

-  The 37th Northeast Regional Meeting, Potsdam, NY, June 2-5, 2010 

- The 238th ACS National Meeting, Washington, DC, August 16-20, 2009 

- CAMP Annual Meeting, Canandaigua, NY, May 14, 2009 

- The 236th ACS National Meeting, Philadelphia, PA, August 17-21, 2008 

- The 35th ACS-Northeast Regional Meeting (NERM),Burlington, VT, June 29 - July 2, 2008 

- The 40th Middle Atlantic Regional Meeting, Bayside, NY, May 17–21, 2008 

- The 234th ACS National Meeting, Boston, MA, August 19-23, 2007 

Cristina, joined Andreecu Lab. in 2006, and

the BIOsem group starts to grow ...