Cristina R. Ispas

Thesis: Biosensors based on inorganic nanoparticles with

biomimetic properties: biomedical applications and in

vivo cytotoxicity measurements

Research: - Electrochemical studies of ceria as electrode material for sensing and biosensing applications

- Cerium oxide and titanium oxide nanomaterials for biosensors design and enzyme immobilization

- Electrochemical sensors for monitoring neurological activity during ischemic brain injury

- Monitoring the level of brain glutamate with implantable Pt microbiosensors

- Investigating the potential risk posed by engineered nanomaterials using zebrafish embryos as a toxicological target

Awards and honors:

  • Best Poster Award- for the Most Attractive Poster, CAMP Annual Technical Meeting, Canandaigua, May 14, 2009

  • Research intern fellow - Procter & Gamble (R&D Fabric and Home Care Division) , June - August, 2008

  • Best Poster Award, CAMP Annual Technical Meeting, Canandaigua, May 16, 2008


US Patent: Reagentless ceria based colorimetric sensor, 2019

E. Silvana Andreescu, M. Ornatska, C.R. Ispas and D. Andreescu


[10] Glutamate oxidase biosensor based on mixed ceria and titania nanoparticles for the detection of glutamate in hypoxic environments

E.R. Ozel, C.R. Ispas, M. Ganesana, J.C. Leiter, and S. Andreescu

Biosens. Bioelectron., 52, 2014, 2240-2249

[9] Review: Recent developments in enzyme-based biosensors for biomedical applications

C.R. Ispas, G. Crivat, and S. Andreescu

Anal. Lett., 45, 2012, 168-186, (Invited)

[8] Chapter 9 - Nanostructured Bioassemblies for Environmental Bioremediation

S. Andreescu, C. Ispas, A. Scangas, and L. Stanciu

in: Nanotechnology for Environmental Decontamination, Eds. M.K. Ram, S. Andreescu and H. Ding, McGraw-Hill, 2011

[7] Biomagnetic capsules for easy removal of phenol and bisphenol A

C.R. Ispas, M.T. Ravalli, A. Steere, and S. Andreescu

Water Res., 44, 2010, 1961-1969

[6] Toxicity and developmental defects of different sizes and shape nickel nanoparticles in zebrafish

C. Ispas, D. Andreescu, A. Patel, D.V. Goia, K. Wallace and S. Andreescu

Environ. Sci. Technol., 43(16), 2009, 6349-6356

[5] Enzyme functionalized mesoporous silica for bioanalytical applications

C. Ispas, I. Sokolov, and S. Andreescu

Anal. Bioanal. Chem., 393(2), 2009, 543-554

(Top 9 most cited articles published in 2009)

[4] Applications of advanced nanomaterials for environmental monitoring

S. Andreescu, J. Njagi, C. Ispas, and M. Ravalli

J. Environ. Monit., 11, 2009, 27-40. (Critical review)

(JEM Spotlight article, Top 10 most accessed articles in 2009 and 2010)

[3] Chapter VII - Nanostructured materials for enzyme immobilization and biosensors

S. Andreescu, J. Njagi, and C. Ispas

in: The New Frontiers of Organic and Composite Nanotechnology, (Eds. V. Erokin, M. K. Ram and O. Yavuz), Elsevier, 2008, 355-394

[2] Mixed Ceria Based Metal Oxides Biosensor for Operation in Oxygen Restrictive Environments

J. Njagi, C. Ispas, and S. Andreescu

Anal. Chem., 80(19), 2008, 7266-7274

[1] Electrochemical Studies of ceria as electrode material for sensing and biosensing applications

C. Ispas, J. Njagi, and S. Andreescu

J. Electrochem. Soc., 155(8), 2008, F169-F176


  • Oral presentations:

- invited speaker -"Enzyme based sensors and colorimetric detection kits for clinical monitoring"

Beckman Coulter Headquarters, Brea CA, April 30, 2010

- invited speaker - "Nanomaterials for enzyme immobilization and biosensor design"

Department of Physiology Johns Hopkins University School of Medicine, Baltimore, MD, March 10, 2010

- "Inexpensive, rapid, and portable bioassay for rapid detection of estrogenic activity",

The 240th ACS National Meeting, Boston MA, August 22-26, 2010

  • Meetings with poster presentations:

- The 240th ACS National Meeting, Boston MA, August 22-26, 2010

- The 37th Northeast Regional Meeting, Potsdam, NY, June 2-5, 2010

- The 238th ACS National Meeting, Washington, DC, August 16-20, 2009

- CAMP Annual Meeting, Canandaigua, NY, May 14, 2009

- The 236th ACS National Meeting, Philadelphia, PA, August 17-21, 2008

- The 35th ACS-Northeast Regional Meeting (NERM),Burlington, VT, June 29 - July 2, 2008

- The 40th Middle Atlantic Regional Meeting, Bayside, NY, May 17–21, 2008

- The 234th ACS National Meeting, Boston, MA, August 19-23, 2007

Cristina, joined Andreecu Lab. in 2006, and

the BIOsem group starts to grow ...